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Case Report
A Case of Autoimmune Hemolytic Anemia Associated with Acute Viral Hepatitis B.
Chong Kyu Woo, Eun Kyung Choi, Hae Ryung Chung, Dong Heuk Keum
Clin Exp Pediatr. 1987;30(9):1034-1039.   Published online September 30, 1987
We experienced a case of autoimmune hemolytic anemia in 3-year-old male patient associated with acute viral hepatitis B. Characteristic findings of this disease are pallor, fever, tachycardia, jaundice, hemoglobinuria, of which the onset is acute or chronic. Although the pathogenic mechanism of this disease is uncertain, it can be associated with pneumonia, measles, varicella, viral hepatitis (50%) and underlying autoinunune deficiency (32%). Diagnosis...
A Case of Gaucher's Disease.
Hyo Nam Cho, Myung Cheol Cho, Hyung Ro Moon, Je Geun Chi, Hyo Min Kim
Clin Exp Pediatr. 1987;30(7):784-790.   Published online July 31, 1987
We experienced a case of Gaucher’s disease of acute infantile type in a 12 month old male boy. The patient showed hepatosplenomegaly with anemia and thrombocytopenia, developmental delay and frequent infection. There were characteristic Gaucher’s cells in bone marrow aspiration and biopsy of liver, spleen, & lymph node. Splenectomy was done at 25 month old. He expired 3 days after splenectomy. Autopsy was done....
A Case of Gaucher's Disease.
J S Kim, S J Kim, H J Suh, I J Kang, S Y Chung, J B Park, S K Moon, S Y Kim
Clin Exp Pediatr. 1986;29(9):1028-1034.   Published online September 30, 1986
We experienced a case of adult type Gaucher's disease in 14 month old male. The patient showed hepatosplenomegaly with anemia and characteristic Gaucher cells in bone marrow aspiration and biopsy of liver and spleen both in light microscopic and electromicroscopic examination. Splenectomy was followed by improvement of anemia and thrombocytopenia but hepatomegaly remained even progressed. A brief review of literature was...
A Case of Autoimmune Hemolytic Anemia Caused by Warm Antibody.
Sei Hee Choi, Mee Kyung Namgoong, Baek Keun Lim
Clin Exp Pediatr. 1986;29(8):898-901.   Published online August 31, 1986
We reviewed a case of autoimmune hemolytic anemia caused by warm antibody in 7years old male patient. Diagnosis was established by clinical features, physical findings, laboratory findings, such as, CBC, Coombs’ test, fragility test, and bone marrow aspiration. Literatures were briefly reviewed.
Original Article
A Comparative Study on Serum Ferritin Concentrations in Anemic Patients Various Diseases.
Sei Woo Chung, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1986;29(7):730-739.   Published online July 31, 1986
Ferritin is a high-molecular weight iron compound consisting of a protein shell, which has normally been considered as a storage compound from which iron is readily mobilized either into the transferrin-bound plasma pool or for intracellular heme synthesis. For comparison of serum ferritin concentrations in anemic patients of various diseases, we measured serum ferritin concentrations, serum iron concentrations, total iron...
Clinical Study on Anemia in Neonatal Period.
Jin Young Lee, Hong Kun Kim, Woo Gil Lee, Soo Jee Moon, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1986;29(5):525-534.   Published online May 31, 1986
Neonatal period is marked with constantly changing hematologic process due to a number of physiologic and pathologic factors, and with risk of underdiagnosis or misdiagnosis of anemia of various causes. Therefore, prompt diagnosis of anemia and accurate identification of its underlying causes would be essential to arrive at the appropriate management and to avoid occasional serious complications. 104 full term...
Bone Marrow Cell Culture(GM-CFU) in Anaplastic Anemia of Children.
Jae Sun Jung, Chang Yee Hong
Clin Exp Pediatr. 1985;28(9):888-898.   Published online September 30, 1985
Bone marrow cell cultures (GM-CFU) were performed in the 15 cases of children with aplastic anemia and the correlation with the clinical course were investigated. They have been treated with androgen with or without low dose prednisone and supportive care. Bone marrow cell cultures from 8 children without any evidence of aplastic anemia were performed as a control. 1)In control...
Case Report
Three Cases of Congenital Hypoplastic Anemia.
Heui Jeong Kwon, Myung Hyun Lee, Jung Hwan Choi, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1985;28(8):829-835.   Published online August 31, 1985
Congenital hypoplastic anemia is a rare disease characterized by aplasia or severe hypoplasia of the erythron, with onset usually at birth or during early infancy. This report presented three cases of congenital hypoplastic anemia in 3 infants with pallor and irritability which were noticed since one to three months of age. Three cases were treatsd with prednisolone and the courses of...
A Case of Congenital Hypoplastic Anemia.
Sae Jin Lee, Moon Chung Cho, Kyung Sook Cho, Doo Sung Moon, Chong Dae Cho
Clin Exp Pediatr. 1985;28(8):801-804.   Published online August 31, 1985
We observed a case of congenital hypoplastic anemia in a 10 month old male patient who was diagnosed through bone marrow aspiration. This steroid-unresponsive patient has been maintaining a concentration of hemoglobin compatible with health from supportive transfusion therapy. A brief review of related literature was made.
A Case of Congenital Nonspherocytic Hemolytic Anemia.
Tae Sook Kim, Sang Bae Jeon, Bok Yang Pyun
Clin Exp Pediatr. 1985;28(6):597-603.   Published online June 30, 1985
We observed a case of congenital nonspherocytic hemolytic anemia who was a 24 month old boy with the signs of jaundice 技 pallor. Evidences of the same disease was also found in the patient' s elder brother & father. We diagnosed these cases by history & physical examination, peripheral & B.M. blood smears, osmotic fragility test, autohemolysis test and etc. A...
Two cases of Aplastic Anemia Following Hepatitis.
Chang Yeol Jeon, Beyung Sang Choi, Hyeon Sook Lee, Jung Soo Kim
Clin Exp Pediatr. 1985;28(1):73-77.   Published online January 31, 1985
Recently, we experienced two cases of aplastic anemia following hepatitis in 6 and 12year old boys. A 6 year old boy was admitted to Jeonbug National University Hospital in Dec. ’82, because of frequent expistaxis and petechiae on entire body. He had a history of hepatitis 2 months ago. On admission liver function was normal and pancytopenia was revealed. Bone...
Original Article
Clinical Study of Childhood Aplastic Anemia.
Sung Won Kim
Clin Exp Pediatr. 1984;27(12):1192-1201.   Published online December 31, 1984
The author reviewed the clinical findings of the 53 children diagnosed as aplastic anemia at the pediatric department of St. Benedict Hospital and W.M. Baptist Hospital, Busan, during a period of 12 years from January 1971 to December 1982. The results were summarized as follows: 1) Among the 53 children with aplastic anemia, the ratio between male and female was1.4 : 1. The male was...
Case Report
Two Case of Aplastic Anemia Following Hepatitis.
Mi Sook Park, Seung Ha Rheu, Young Gun Kim, Baek Keaun Lim, Jong Soo Kim
Clin Exp Pediatr. 1984;27(8):808-813.   Published online August 31, 1984
Aplastic Anemia following Hepatitis is an uncommon disease and it has a poor prognosis. Recently the authors experienced two cases of aplastic anemia following hepatitis in a 13 year old girl and a 14 year old boy. The thirteen year old girl was admitted following 2 months of Jaundice and 1 day df epistaxis. . At admission, pancytopenia developed and her...
Original Article
A Clinical Observation of Anemia in Children.
Tae Sook Kim, Sang Bae Jeon, Bok Yang Pyun
Clin Exp Pediatr. 1984;27(8):772-777.   Published online August 31, 1984
We have observed clinically about 161 cases of anemia among 251 patients who were admitted to Y.D.P.C.H. The results were obtained as follows: 1)The incidence of anemia among total admitted patients (251) was 64.1% (161 cases). These were grouped into mild & moderate anemia(58.2%) and severe anemia (5.9%) on the base of hemoglobin level. 2)The sex ratio was aproximatly 1.5 : 1...
Case Report
Two Cases of Gaucher's Disease in Brothers.
Jeong Sick Min, Il Whan Kim, Dae Young Hwang, Hyun Gi Jeong, Jae Sun Park, In Sun Jun, Man Ha Huh
Clin Exp Pediatr. 1984;27(6):628-634.   Published online June 30, 1984
We experienced 2 cases of Gaucher' s disease of adult type in brothers when their ages were 4 year 1 month and 3 year 10 month respectively. They showed remarkable hepatosplenomegaly with mild hematologic complications and characteristic histiocytoid cells in the spleen and liver biopsies. Splenectomy was followed by improvement of anemia and labored respiration in both patients. In case...
Fanconi's Anemia.
J H Yoo, E M Kim, S J Lee, W B Kim, D W Lee, D Y Kang, K Y choi
Clin Exp Pediatr. 1983;26(11):1139-1144.   Published online November 30, 1983
We report 1 case of Fanconi’s anemia which has severe pancytopenia, increased fetal Hb, hyperpigmented skin, absence of right thumb and metacarpal bone, retardation of bone age and chromosomal abnormalities with a brief review of related literature and references.
A Case of Aplastic Anemia Following Hepatitis.
Woo Yeong Chung, Seung Won Park, In Soon Park, Chul Ho Kim, Soo Yong Lee
Clin Exp Pediatr. 1983;26(8):812-815.   Published online August 31, 1983
We experienced a case of aplastic anemia following hepatitis in a 11-year old male child. He was admitted because of pallor and gum bleedings with an episode of hepatitis 2 months prior to this admission. On admission CBC showed pancytopenia and there was marked hypocellularity of all hematopoietic elements in bone marrow aspiration. Transfusion and treatment with prednisolone and oxymetholone were tried but...
A Case of Fanconi's Anemia.
Dong Hwan Cha, Jung Shim Choi, Kwang Ho Kim, Hong Ku Lee, Sha Sook Hahn
Clin Exp Pediatr. 1983;26(8):808-811.   Published online August 31, 1983
Recently we experienced a case of Fanconist anemia in a 6 years old male child and reported with brief reviews of literatures. The initial symptom was nasal bleeding and pallor which observed between age of 4 years to 6 years. He was microcephaly, His both thumbs were rudimentary. Cystogenic study showed chromosomal breakage. Bone marrow study showed hypocellularity.
A Case of Congenital Hypoplastic Anemia.
D S Moon, D K Na, J D Jo, I S Jun, M H Huh
Clin Exp Pediatr. 1983;26(5):499-503.   Published online May 31, 1983
The Authors report A Case of Congenital Hypoplastic Anemia with congenital megacoloit in a about one month old male infant who was admitted because of abdominal distension, failure of passing meconium for 96 hours and pale anemic face. This syndrome was diagnosed by clinical and laboratory findings: normochromic anemia, reticulocytopenia, developing early infant, bone marrow with normal cellularity and deficiency of red cell precursor. A...
A Case Report of Congenital Hypoplastic Anemia.
Hyun Gi Jung, Tai Gyo Whang, In Soon Park, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1983;26(3):279-283.   Published online March 31, 1983
We observed a case of congenital hypoplastic anemia in 22 months old Korean male infant whose clinical and hematologic improvement was achieved by administration of prednisone. A brief review of related literatures was made.
A Case of Congenital Hypoplastic Anemia.
Young Jong Woo, Jae Sook Ma, Tai Ju Hwang
Clin Exp Pediatr. 1983;26(2):188-192.   Published online February 28, 1983
Authors have observed a case of congenital hypoplastic anemia in 18 months old male patient who was diagnosed through the bone marrow aspiration. The liver was enlarged and the biopsy specimen disclosed iron deposition in the hepatocyte, which was thought to be resulted from multiple blood transfusion and administration of iron preparation. A brief review of related literature was made.
Original Article
A Study on Purpura in Children.
Jong Sub Lee, Kyung Ho Kim, Ki bok Kim
Clin Exp Pediatr. 1983;26(2):151-157.   Published online February 28, 1983
We have seen 96patients who were admitted with purpura to the Pediatric Department of Kwangju Christian Hospital during the period of 10 years from Jan., 1971 to Dec., 1980. The following observations were made; 1) Leukemia(26 cases, 27.0%) was the most common underlying disease, followed by allergic purpura (25 cases, 26.0%), idiopathic thrombocytopenic purpura (22 cases, 22.9%), Aplastic Anemia (13 cases, 13.5%), sepsis (5 cases,...
Case Report
A Case of Aplastic Anemia Following Hepatitis.
Chul Ho Lee, Hyo Jyung Kim, Hye Kyung Lee, Soon Jae Lee
Clin Exp Pediatr. 1983;26(1):81-85.   Published online January 31, 1983
A case of aplastic anemia following hepatitis is presented. A 13-year-old boy was admitted due to unexpected bleeding manifestations after recovery from hepatitis. There was marked pancytpenia and examiation of bone marrow revealed remarkable hypoplasia. His clinical course became worsened despite antibiotics, multiple transfusions and therapy with corticosteroid, oxymetholone. Related literatures are also briefly reviewed.
Original Article
A study in The Changes of Platelet Count in iron Deficiency Anemia among Children.
Nam Ae Kim, Kir Young Kim
Clin Exp Pediatr. 1982;25(10):1015-1021.   Published online October 31, 1982
Iron deficiency anemia (IDA) is the most common nutritional anemia among chidren. A study on the changes of platelet count in IDA was conducted with 83 children who were diagnosed at the Severance Hospital in a 5 J/2-year pericd from Jan. 1975 to Jun. 1981. The results are summarized as follows. 1. IDA was most common among chidren younger than 2-years(61%) due to nutritional deficiency. It...
Study on cord blood hemoglobin and etiology of neonatal anemia.
Chul Lee, Hae Jung Cho, Myung Ho Lee, Sook Ja Park, Young Hae Lee
Clin Exp Pediatr. 1982;25(9):906-913.   Published online September 30, 1982
Capillary samples obtained by skin prick, generally from the heel or toe, have a higher hemoglobin Concentration than simultaneously collected venous samples. So, capillary values should not be compared to previously obtained cord venous blood values when one is looking for changes in hemoglobin, concentration during the first week of life. Cord venous blood hemoglobin and hemotocrit of 309 normal newborn infants have been...
Incidenc of Iron Deficiency Anemia and Changes in Serum Feffitin Level in Various Childhood Diseases.
Hak Sunh Kim, Kwang Joo Rhee, Tae Won Kim
Clin Exp Pediatr. 1982;25(8):800-806.   Published online August 31, 1982
A serum ferritin level is now the most sensitive and specific assay for iron deficiency. Incidence of iron deficiency anemia was determined by means of the serum ferritin level and the response to iron therapy, and changes in serum ferritin level were observed in 421 hospitalized pediatric patients with various diseases. The results were as follows : 1. Incidence of...
Anemia in the Metal and Physical Handicapped.
Jeong Sik Min, Chan Il Ahn
Clin Exp Pediatr. 1982;25(7):687-698.   Published online July 31, 1982
Nutrition is thought to be much more important to the handicapped for their growth and development and successful management of their disease because they have much more complexed problems in physical, emotional, familial, and socioeconomic aspects. The authors determined number of erythrocytes and leukocytes, quantity of hemoglobin, hematocrit, reticulocyte, number of platelets for the survey of anemia to evaluate the...
Case Report
Congenital Hiatal Hernia Associated with Anemia.
Young Sook Hong, Young Mo Sohn, Pyung Kil Kim
Clin Exp Pediatr. 1982;25(5):523-527.   Published online May 31, 1982
Surgically corrected congenital hiatal hernia associated with anemia has been presented. A 1 year old boy has been complained of severe pallor and fever on admission. Reentgenologic examination revealed thoracic stomach and then the hernia was repaired by transabdominal approach. It was found to be a paraesophageal type hiatal hernia. Pathogenesis and complications of congenital histal hernia were discussed and...
A Case of Kasabach-Merritt Syndrome.
Young Yoon choi, young Hwa park, Hyung Suk byun, Chull sohn, Ae Sook kim
Clin Exp Pediatr. 1982;25(3):310-316.   Published online March 31, 1982
Hemangioma associated with thrombocytopenia is a relatively rare occurrence. The first case was described in 1940 by Kasabach and Merritt, who used X-ray therapy as radium implants in the treatment of hemangioma on the affected infant. The tumor regressed and the platelet count rose to normal. Mechanical sequestration of platelets in the vascular channels of the hemangioma is believed to be the mechanism of...
Original Article
Clinical Observation of Hemolytic Anemia in Children Except Isoimmunization.
Hak Yong Kim, Young Mo Sohn, Kwan Sub Chung, Kir Young Kim, Duk Jin Yun
Clin Exp Pediatr. 1981;24(12):1149-1156.   Published online December 15, 1981
Hemolytic anemia is caused by early destruction of red cells and there are many etiologies,ecently, prosthetic devices are used frequently to correct cardiac diseases and they also cause hemolytic anemia. We performed clinical analysis of 74 patients with hemolytie anemia who had been diagnosed at Severance hospital in recent 10 years. Results were as follows: 1)In 74 cases, male were 46...
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